M111L (p.Met111Leu) variant of ABCB1 (ATP-dependent translocase ABCB1)
M111L (p.Met111Leu) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
M111L (p.Met111Leu) variant details
- p.Met111Leu
- ExAC rs761202837
- TOPMed rs761202837
- gnomAD rs761202837
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- CADD 21.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available