M105L (p.Met105Leu) variant of ABCB1 (ATP-dependent translocase ABCB1)
M105L (p.Met105Leu) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
M105L (p.Met105Leu) variant details
- p.Met105Leu
- ExAC rs765543439
- TOPMed rs765543439
- gnomAD rs765543439
- Missense
- Variant Prioritization Score for Impact Estimate 0.0633
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the REMAINING population (allele frequency 8.3e-05)
- Structural context available