L88R (p.Leu88Arg) variant of ABCB1 (ATP-dependent translocase ABCB1)
L88R (p.Leu88Arg) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
L88R (p.Leu88Arg) variant details
- p.Leu88Arg
- gnomAD rs1257387920
- Missense
- Variant Prioritization Score for Impact Estimate 0.0562
- CADD 0.19
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available