K28T (p.Lys28Thr) variant of ABCB1 (ATP-dependent translocase ABCB1)
K28T (p.Lys28Thr) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K28T (p.Lys28Thr) variant details
- p.Lys28Thr
- TOPMed rs112801674
- gnomAD rs112801674
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available