I59V (p.Ile59Val) variant of ABCB1 (ATP-dependent translocase ABCB1)
I59V (p.Ile59Val) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I59V (p.Ile59Val) variant details
- p.Ile59Val
- TOPMed rs1584902458
- Missense
- Variant Prioritization Score for Impact Estimate 0.0773
- CADD 0.62
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available