G10R (p.Gly10Arg) variant of ABCB1 (ATP-dependent translocase ABCB1)
G10R (p.Gly10Arg) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G10R (p.Gly10Arg) variant details
- p.Gly10Arg
- gnomAD rs1457629148
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- CADD 10.70
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available