G10E (p.Gly10Glu) variant of ABCB1 (ATP-dependent translocase ABCB1)
G10E (p.Gly10Glu) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
G10E (p.Gly10Glu) variant details
- p.Gly10Glu
- gnomAD rs1348388210
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- CADD 6.55
- PolyPhen-2 0.00
- SIFT 0.43
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available