F17S (p.Phe17Ser) variant of ABCB1 (ATP-dependent translocase ABCB1)
F17S (p.Phe17Ser) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
F17S (p.Phe17Ser) variant details
- p.Phe17Ser
- ExAC rs763540261
- gnomAD rs763540261
- Missense
- Variant Prioritization Score for Impact Estimate 0.0606
- CADD 1.05
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available