D6Y (p.Asp6Tyr) variant of ABCB1 (ATP-dependent translocase ABCB1)
D6Y (p.Asp6Tyr) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D6Y (p.Asp6Tyr) variant details
- p.Asp6Tyr
- ExAC rs780204251
- gnomAD rs780204251
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- CADD 22.30
- PolyPhen-2 0.13
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available