D110G (p.Asp110Gly) variant of ABCB1 (ATP-dependent translocase ABCB1)
D110G (p.Asp110Gly) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D110G (p.Asp110Gly) variant details
- p.Asp110Gly
- TOPMed rs201389507
- gnomAD rs201389507
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- CADD 18.40
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available