T1025S (p.Thr1025Ser) variant of PIK3CA (P42336)
T1025S (p.Thr1025Ser) in PIK3CA (P42336) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Endometrial carcinoma. The record also includes structural context.
T1025S (p.Thr1025Ser) variant details
- p.Thr1025Ser
- NCI-TCGA Cosmic COSV5587
- NCI-TCGA Cosmic COSV5591
- NCI-TCGA Cosmic COSV5595
- Ensembl rs397517202
- Likely pathogenic
- Endometrial carcinoma
- Missense
- ClinVar: Likely pathogenic (Endometrial carcinoma)
- EBI: Pathogenic (in MCAP)
- UniProt: Pathogenic (in MCAP)
- Structural context available